Pipeline

Cancer vaccine 

Tumor, DCs

Immuno-stimulating gene, transcription factor (+/- tumor associated antigens)

Preclinical: cell line data

Oncolytic vaccinia virus in combination of anti-PD-1 against bladder cancer

Tumor, tumor associated vasculature

Cytokines

Preclinical: cell and animal data

In vivo transduction vector for CAR- or TCR-T cells (oncology & immunology)

T-Cells

Cytokines and CAR- or TCR-construct

Preclinical: validated in cells

Oncolytic vaccinia virus for systematic delivery

Tumor, Tumor associated vasculature

Immunogenic cell death, checkpoint inhibitor, fusogenic

Preclinical: validated in animal models